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Table 1 Study subject characteristics for Endoscopy II overall, and for the current study subsets

From: Discovery and validation of a colorectal cancer classifier in a new blood test with improved performance for high-risk subjects

 

Endo II

CRC ITT discovery set

CRC ITT validation set

All

Control

Disease

Control

Disease

Total

4698

2759

340

1189

147

Clinic number: #

31

605

340

53

135

26

32

299

171

13

81

9

33

966

579

71

249

21

34

300

190

18

65

12

35

957

564

72

240

34

36

858

510

48

248

17

37

713

405

65

171

28

Age: years

Mean

63.5

62.7

69.7

62.9

70.1

Standard deviation

12.6

12.6

10.6

12.7

10.7

Median

64.3

63.6

69.5

63.3

71.5

Minimum

18.1

20.1

37.5

18.1

23.6

Maximum

96.0

96.0

94.8

93.3

89.1

Gender: # (%)

Female

2455 (52.3)

1473 (53.4)

144 (42.4)

650 (54.7)

55 (37.4)

Male

2243 (47.7)

1286 (46.6)

196 (57.6)

539 (45.3)

92 (62.6)

BMI: kg/m 2

Mean

25.6

25.6

25.5

25.5

26.2

Standard deviation

4.6

4.7

4.7

4.5

3.9

Median

25.1

25.1

24.8

25.0

25.7

Minimum

11.7

13.0

15.8

11.7

16.9

Maximum

50.5

50.2

47.1

50.5

39.1

CRC stage: # (%)

I

101 (19.8)

0 (0)

74 (21.8)

0 (0)

25 (17.0)

II

163 (31.9)

0 (0)

105 (31.0)

0 (0)

50 (34.0)

III

139 (27.2)

0 (0)

87 (25.7)

0 (0)

45 (30.6)

IV

108 (21.1)

0 (0)

73 (21.5)

0 (0)

27 (18.4)

Diagnosis: # (%)

Colon cancer

319 (6.8)

0 (0)

211 (62.1)

0 (0)

92 (62.6)

Rectal cancer

193 (4.1)

0 (0)

129 (37.9)

0 (0)

55 (37.4)

Adenoma colon

515 (11.0)

340 (12.3)

0 (0)

148 (12.4)

0 (0)

Adenoma rectum

174 (3.7)

117 (4.2)

0 (0)

51 (4.3)

0 (0)

No comorbidity-no finding

1164 (24.8)

763 (27.7)

0 (0)

334 (28.1)

0 (0)

Comorbidity-no finding

814 (17.3)

534 (19.4)

0 (0)

229 (19.3)

0 (0)

Other cancer

177 (3.8)

119 (4.3)

0 (0)

50 (4.2)

0 (0)

Other finding

1342 (28.6)

886 (32.1)

0 (0)

377 (31.7)

0 (0)