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Table 2 The difference of protein expression in cancer and non-cancerous tissues for HCC with or without portal vein thrombosis

From: Down-regulation of metabolic proteins in hepatocellular carcinoma with portal vein thrombosis

Spot

Protein name

Accession number

Theoretical (MW/PI)

Mascot score

Coverage (%)

Protein expression (folds)

N: T (p)

N-PVT: T-PVT (p)

T: T-PVT (p)

1717

Elongation factor 2

P13639

95,146/6.42

188

35

−1.16 (0.650)

−2.63 (0.004)

−1.43 (0.156)

2961

Fumarate hydratase

P07954

54,602/8.85

72

24

1.62 (0.256)

2.16 (0.017)

1.98 (0.088)

2966

Betaine–homocysteine S-methyltransferase 1

Q93088

45,426/6.7

66

30

2.64 (0.004)

4.59 (0.001)

4.30 (0.097)

3132

Isovaleryl-CoA dehydrogenase

P26440

46,803/9.3

120

35

2.13 (0.036)

3.56 (<0.001)

1.83 (0.099)

3198

Short-chain specific acyl-CoA dehydrogenase

P43155

44,611/9.1

112

35

1.56 (0.023)

3.16 (0.011)

2.38 (0.026)

3242

Arginase-1

P05089

34,713/6.87

174

52

2.67 (<0.001)

3.75 (<0.001)

2.36 (0.049)

3895

Carbonic anhydrase 1

Q13162

28,721/6.63

112

52

1.00 (0.997)

3.98 (0.001)

4.05 (0.004)

3948

Endoplasmic reticulum protein ERp29

P00915

29,032/7.5

88

40

1.89 (0.030)

3.47 (0.008)

1.89 (0.198)

4003

Peroxiredoxin-4

P30040

30,749/5.8

110

49

1.91 (0.102)

2.19 (0.002)

1.16 (1.000)

4048

Dihydropteridine reductase

P09417

26,001/7.8

70

46

1.30 (0.143)

2.29 (0.008)

1.61 (0.153)

  1. N non-cancerous tissue in HCC without portal vein thrombosis, T cancer tissue in HCC without portal vein thrombosis, N-PVT non-cancerous tissue in HCC with portal vein thrombosis, T-PVT cancer tissue in HCC with portal vein thrombosis