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Fig. 4 | Clinical Proteomics

Fig. 4

From: Proteomic profiling identifies markers for inflammation-related tumor–fibroblast interaction

Fig. 4

Consensus Molecular Subtype Classification of upregulated stromal markers and SerpinB5 [34]. For comparing gene expression between the subtypes and selected markers, raw data of published data sets were obtained as used in the consensus subtype classification of CRC [34], processed, analyzed and differences plotted as log2-foldchange (log2-FC). a–e expression of 5 selected stromal markers that were upregulated on protein level in our data set. f results for SerpinB5, a parenchymal derived marker. Statistical analysis of log2-foldchanges were performed by using empirical Bayesian statistics. Adjusted p values were < 0.001 except for those marked non-significant (ns)

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