Proteomic profiling identifies markers for inflammation-related tumor–fibroblast interaction

Table 3 Macrophage and mast cell markers

Acc.	Gene names	MP significant	Tumor versus normal		High versus low		Low versus normal		SC (Isella et al. 2015)
Acc.	Gene names	MP significant	log2FC	p value	log2FC	p value	log2FC	p value	SC (Isella et al. 2015)
P22897	MRC1	+^a	− 1.266	0.015	2.396	0.000	− 2.464	0.000	1.000
Q15661	TPSAB1	+	− 1.910	0.001	2.446	0.001	− 3.133	0.000	0.920
P15088	CPA3	+	− 2.581	0.000	2.481	0.003	− 3.821	0.000	0.994
P23946	CMA1	+	− 3.523	0.000	3.929	0.001	− 5.487	0.000	1.000

Higher abundance of mast cell markers in normal compared to tumor tissue indicated by negative log2-foldchanges. Note the higher abundance of these markers in tumors of high stage patients. Stromal contribution reprinted by permission from Macmillian Publishers Ltd: Nature Genetics (47: 312–319), copyright (2015)
^aOnly low-stage versus normal is MP significant

ISSN: 1559-0275