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Table 2 The Distribution of the ≥ 510 gene symbols observed from the endogenous tryptic peptides of normal human plasma identified by X!TANDEM with respect to the human Gene Ontology (GO) Biological Processes as computed by STRING V10

From: The proteins cleaved by endogenous tryptic proteases in normal EDTA plasma by C18 collection of peptides for liquid chromatography micro electrospray ionization and tandem mass spectrometry

Term

Number of genes

p-value

p-value_fdr

p-value_bonferroni

Multicellular organismal catabolic process

29

1.97E−27

1.71E−23

2.65E−23

Collagen catabolic process

28

2.55E−27

1.71E−23

3.43E−23

Collagen metabolic process

28

1.09E−25

4.90E−22

1.47E−21

Multicellular organismal metabolic process

29

2.76E−25

9.28E−22

3.71E−21

Multicellular organismal macromolecule metabolic

28

1.01E−24

2.72E−21

1.36E−20

Extracellular matrix organization

46

2.92E−22

6.34E−19

3.93E−18

Extracellular structure organization

46

3.30E−22

6.34E−19

4.43E−18

Extracellular matrix disassembly

29

1.28E−21

2.16E−18

1.73E−17

Neuron differentiation

56

1.36E−12

2.04E−09

1.83E−08

Neuron development

50

1.93E−12

2.60E−09

2.60E−08

Cellular component organization

151

8.25E−12

1.01E−08

1.11E−07

Axon guidance

34

2.42E−11

2.50E−08

3.25E−07

Cellular component organization or biogenesis

152

2.86E−11

2.75E−08

3.85E−07

Neuron projection morphogenesis

38

1.03E−10

9.22E−08

1.38E−06

Axon development

37

1.32E−10

1.11E−07

1.78E−06

Axonogenesis

36

1.50E−10

1.18E−07

2.02E−06

Cellular component disassembly

37

1.57E−10

1.18E−07

2.12E−06

Cell morphogenesis involved in neuron differentiation

37

1.98E−10

1.40E−07

2.66E−06

Generation of neurons

61

2.17E−10

1.46E−07

2.92E−06

Neurogenesis

63

2.85E−10

1.83E−07

3.84E−06

Neuron projection development

41

3.76E−10

2.30E−07

5.06E−06

Nervous system development

80

5.28E−10

3.09E−07

7.10E−06

Cell development

69

8.28E−10

4.64E−07

1.11E−05

Cell projection morphogenesis

41

1.81E−09

9.75E−07

2.44E−05

Cell part morphogenesis

41

4.63E−09

2.40E−06

6.23E−05

Collagen fibril organization

10

6.19E−09

3.08E−06

8.33E−05

Locomotion

55

7.21E−09

3.47E−06

9.70E−05

Chemotaxis

37

1.07E−08

4.80E−06

1.44E−04

Taxis

37

1.07E−08

4.80E−06

1.44E−04

Movement of cell or subcellular component

58

1.16E−08

5.02E−06

1.56E−04

System development

116

1.38E−08

5.81E−06

1.86E−04

Cell morphogenesis involved in differentiation

38

1.92E−08

7.81E−06

2.58E−04

Single-organism catabolic process

41

2.45E−08

9.70E−06

3.30E−04

Single-organism metabolic process

116

3.70E−08

1.42E−05

4.98E−04

Cell projection organization

45

9.88E−08

3.69E−05

1.33E−03

  1. The headings are exactly as supplied by STRING. The Filtered (Filter 2) data can be found in Additional file 1, Additional file 2, Additional file 3, Additional file 4