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Table 1 Baseline patient characteristics

From: The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature

Characteristics All patients
23 (100)a
NR
7 (30)
PR
10 (43)
TR
6 (26)
p valueb
Age (years)      
 Median 58.6 ± 11.1 54.7 ± 14.3 59.7 ± 10.2 61.3 ± 8.6  
 Range 31–75 31–72 47–75 48–71  
Sex      0.324
 Male 19 (83) 7 (100) 7 (70) 5 (83)  
 Female 4 (17) 0 3 (30) 1 (17)  
Tumor location from anal verge (cm)      0.961
 3–5 10 (43) 3 (43) 5 (50) 2 (33)  
 6–10 11 (48) 3 (43) 4 (40) 4 (67)  
 > 10 2 (9) 1 (14) 1 (10) 0  
Tumor differentiation      0.884
 Missing value 9 (39) 3 (43) 3 (30) 3 (50)  
 Well 5 (22) 2 (29) 2 (20) 1 (17)  
 Moderately 9 (39) 2 (29) 5 (50) 2 (33)  
 Undifferentiated 0 0 0 0  
Pre-treatment stage      0.441
 IIA 3 (13) 0 2 (20) 1 (17)  
 IIIA 1 (4) 0 1 (10) 0  
 IIIA–IIIB 2 (9) 0 0 2 (33)  
 IIIB 4 (17) 1 (14) 2 (20) 1 (17)  
 IIIB–IIIC 12 (52) 5 (71) 5 (50) 2 (33)  
 IIIC 1 (4) 1 (14) 0 0  
iT      0.560
 T2 3 (13) 0 1 (10) 2 (33)  
 T3 18 (78) 6 (86) 8 (80) 4 (67)  
 T4 2 (9) 1 (14) 1 (10) 0  
  1. iT initial tumor, NR non-responders, PR partial responders, TR total responders
  2. aFirst number: number of patients; number in parentheses: percentage of patients
  3. bThe p value is obtained by Fisher’s exact test and is considered significant when p value < 0.05