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Table 1 Baseline patient characteristics

From: The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature

Characteristics

All patients

23 (100)a

NR

7 (30)

PR

10 (43)

TR

6 (26)

p valueb

Age (years)

     

 Median

58.6 ± 11.1

54.7 ± 14.3

59.7 ± 10.2

61.3 ± 8.6

 

 Range

31–75

31–72

47–75

48–71

 

Sex

    

0.324

 Male

19 (83)

7 (100)

7 (70)

5 (83)

 

 Female

4 (17)

0

3 (30)

1 (17)

 

Tumor location from anal verge (cm)

    

0.961

 3–5

10 (43)

3 (43)

5 (50)

2 (33)

 

 6–10

11 (48)

3 (43)

4 (40)

4 (67)

 

 > 10

2 (9)

1 (14)

1 (10)

0

 

Tumor differentiation

    

0.884

 Missing value

9 (39)

3 (43)

3 (30)

3 (50)

 

 Well

5 (22)

2 (29)

2 (20)

1 (17)

 

 Moderately

9 (39)

2 (29)

5 (50)

2 (33)

 

 Undifferentiated

0

0

0

0

 

Pre-treatment stage

    

0.441

 IIA

3 (13)

0

2 (20)

1 (17)

 

 IIIA

1 (4)

0

1 (10)

0

 

 IIIA–IIIB

2 (9)

0

0

2 (33)

 

 IIIB

4 (17)

1 (14)

2 (20)

1 (17)

 

 IIIB–IIIC

12 (52)

5 (71)

5 (50)

2 (33)

 

 IIIC

1 (4)

1 (14)

0

0

 

iT

    

0.560

 T2

3 (13)

0

1 (10)

2 (33)

 

 T3

18 (78)

6 (86)

8 (80)

4 (67)

 

 T4

2 (9)

1 (14)

1 (10)

0

 
  1. iT initial tumor, NR non-responders, PR partial responders, TR total responders
  2. aFirst number: number of patients; number in parentheses: percentage of patients
  3. bThe p value is obtained by Fisher’s exact test and is considered significant when p value < 0.05