Table 1 Intra- and inter-assay variability of serum MALDI-TOF/MS peptidomic patterns, expressed as the median coefficient of variation (CV)
Normalization stategies | Intra-assay CVs Median (IQR) | Inter-assay CVs Median (IQR) |
|---|---|---|
Non-normalized features | 38.16 (33.44–44.50) | 64.12 (53.95–72.23) |
Median normalized features | 24.89 (21.84–29.29) | 35.72 (30.93–47.27) |
Median normalized and sLOD adjusted features | 30.10 (27.37–33.11) | 40.80 (34.64–50.17) |