Fig. 1
From: Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas
a Samples of chRCC tissue or RO tissue were collected from FFPE specimens and, post-trypsination, differentially labeled by isotopic, formaldehyde-based dimethylation. A differentially labeled, pooled reference standard was also included. b > 2400 proteins were identified (false-discovery rate < 1%) and quantified in at least four RO and four chRCC samples. Within this core proteome, each chRCC and RO case contributed a comparable number of protein identifications and quantitations. Also, the log-transformed sample/standard ratios were comparable for all cases. Whiskers extend to data points that are less than 1.5 × IQR away from 1st/3rd quartile. c Supervised partial least squares discriminant analysis separates the RO and chRCC proteome profiles