Table 3 Differences in serum glycopatterns between SCC groups and healthy control by the lectin microarray analysis based on data of 16 lectins giving significant differences

Jacalin

Galβ1-3GalNAcα-Ser/Thr(T), sialyl-T(ST)

0.30***

0.17***

0.23***

HHL

High-Mannose, Manα1-3Man, Manα1-6Man, Man5-GlcNAc2-Asn

2.59*

2.32*

2.52*

MAL-II

Siaα2-3Galβ1-4Glc(NAc)/Glc, SLe^x

0**

0**

0**

PTL-I

GalNAc, GalNAcα-1, 3Gal, GalNAcα-1, 3Galβ-1,3/4Glc

6.63**

6.61***

6.36**

SJA

Terminal in GalNAc and Gal

3.61**

3.37**

3.01**

EEL

Galα1-3(Fucα1-2)Gal

0.66

0.11***

0.14***

LTL

Fucα1-2Galβ1-4GlcNAc, Fucα1-3 (Galβ1-4) GlcNAc

0**

0**

0**

DBA

GalNAcα-Ser/Thr(Tn) and GalNAcα1-3Gal

0*

0^*

0*

RCA-120

β-Gal, Galβ-1, 4GlcNAc (type II), Galβ1-3GlcNAc (type I)

0.44**

0.46***

0.39**

STL

Trimers and tetramers of GlcNAc, core (GlcNAc) of N-glycan, oligosaccharide containing GlcNAc and MurNAc

0.35**

0.31**

0.33**

BS-I

αGal and αGalNAc

/**

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DSA

β-D-GlcNA, (GlcNAcβ1-4)_n, Galβ1-4GlcNAc

4.02***

2.94

3.77***

SBA

Terminal GalNAc (especially GalNAcα1-3Gal)

15.57***

14.21***

13.32***

UEA-I

Fucoseα1-2Galβ1-4GlcNAc

8.00*

8.81***

7.86***

BPL

Galβ1-3GalNAc, terminal GalNAc

/***

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PHA-E+L

Bisecting GlcNAc, biantennary N-glycans and tetraantennary complex-type N-glycan

8.80***

11.52**

9.86**