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Table 2 Estimation of lipid moieties and proteins in blood plasma

From: Lipid metabolism impairment in patients with sepsis secondary to hospital acquired pneumonia, a proteomic analysis

Plasma level median (IQR)

Control (n = 10)

Survivor patients (n = 6)

Non-survivor patients (n = 11)

D0

D7

D0

D7

Total cholesterol (mg/dL)

198

90.5*

110.5*

105*

104*

 

(176.5–245.5)

(79–121.5)

(103–145.5)

(86–125)

(91–150)

HDL-C (mg/dL)

54.5

20*

33.5*

23*

20*

 

(45.8–59.3)

(7.8–33.5)

(17.8–42.5)

(21–35)

(12–48)

LDL-C (mg/dL)

121.5

51*

68*

56*

59*

 

(89–161.3)

(39.8–79)

(56.3–80)

(52–68)

(52–83)

Non-HDL-C (mg/dL)

148

70*

86*

79*

86*

 

(121.8–190.3)

(54–99.5)

(70–109.3)

(72–97)

(77–103)

Triglycerides (mg/dL)

144

89.5

103

125

127

 

(115–184.5)

(64.5–165.3)

(67.5–200)

(85–179)

(106–177)

APO A-I (mg/dL)

151.5

65*

92*

67*

67*

 

(139.8–177.5)

(45.8–88.3)

(58.8–109.8)

(63–88)

(49–91)

APO B (mg/dL)

104

56.5*

72.5*

71*

77

 

(85.5–141.5)

(50.5–73)

(68.3–78.5)

(48–86)

(71–112)

Lipoproteins (mg/dL)

15.5

5.8

5.9

6.5

13.2

 

(8.6–26.9)

(3.27–25)

(4.12–31.6)

(4.9–14.9)

(5.8–36.8)

PON 1 (ng/mL)#

210.2

106.3*

111.9*

110.2*

113.8*

 

(170.1–313.7)

(78.9–141.5)

(83.6–189.4)

(93.5–183.6)

(98.5–174.9)

Haptoglobin (mg/mL)#

0.98

1.6

1.4

1.3

1.5

 

(0.7–1.3)

(0.9–2.1)

(0.8–1.7)

(0.9–1.7)

(1.2–1.6)

  1. *P ≤ 0.05 when comparing patients to healthy volunteers by Kruskal–Wallis test or one-way ANOVA with Bonferroni’s post hoc multiple comparison test
  2. #PON 1 measurements were performed in 11 individuals in control group, 11 in survivors and 12 in non-survivors group; haptoglobin measurements were performed in 8 controls, 4 survivors patients and 10 non-survivors patients