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Table 2 Estimation of lipid moieties and proteins in blood plasma

From: Lipid metabolism impairment in patients with sepsis secondary to hospital acquired pneumonia, a proteomic analysis

Plasma level median (IQR) Control (n = 10) Survivor patients (n = 6) Non-survivor patients (n = 11)
D0 D7 D0 D7
Total cholesterol (mg/dL) 198 90.5* 110.5* 105* 104*
  (176.5–245.5) (79–121.5) (103–145.5) (86–125) (91–150)
HDL-C (mg/dL) 54.5 20* 33.5* 23* 20*
  (45.8–59.3) (7.8–33.5) (17.8–42.5) (21–35) (12–48)
LDL-C (mg/dL) 121.5 51* 68* 56* 59*
  (89–161.3) (39.8–79) (56.3–80) (52–68) (52–83)
Non-HDL-C (mg/dL) 148 70* 86* 79* 86*
  (121.8–190.3) (54–99.5) (70–109.3) (72–97) (77–103)
Triglycerides (mg/dL) 144 89.5 103 125 127
  (115–184.5) (64.5–165.3) (67.5–200) (85–179) (106–177)
APO A-I (mg/dL) 151.5 65* 92* 67* 67*
  (139.8–177.5) (45.8–88.3) (58.8–109.8) (63–88) (49–91)
APO B (mg/dL) 104 56.5* 72.5* 71* 77
  (85.5–141.5) (50.5–73) (68.3–78.5) (48–86) (71–112)
Lipoproteins (mg/dL) 15.5 5.8 5.9 6.5 13.2
  (8.6–26.9) (3.27–25) (4.12–31.6) (4.9–14.9) (5.8–36.8)
PON 1 (ng/mL)# 210.2 106.3* 111.9* 110.2* 113.8*
  (170.1–313.7) (78.9–141.5) (83.6–189.4) (93.5–183.6) (98.5–174.9)
Haptoglobin (mg/mL)# 0.98 1.6 1.4 1.3 1.5
  (0.7–1.3) (0.9–2.1) (0.8–1.7) (0.9–1.7) (1.2–1.6)
  1. *P ≤ 0.05 when comparing patients to healthy volunteers by Kruskal–Wallis test or one-way ANOVA with Bonferroni’s post hoc multiple comparison test
  2. #PON 1 measurements were performed in 11 individuals in control group, 11 in survivors and 12 in non-survivors group; haptoglobin measurements were performed in 8 controls, 4 survivors patients and 10 non-survivors patients