Fig. 1From: Clinical method evaluation of hemoglobin S and C identification by top-down selected reaction monitoring and electron transfer dissociationComplete workflow of the SRM ETD method. a Sample preparation protocol. b Scheme of the data acquisition by TD SRM ETD method and data analysis. Specific EIC for α chain, βA chain, βS chain, βC chain, βE chain. For each chain, the mean pic intensity is obtained and chain ratio is calculated. The detection of each chain is based on a color code and a cut-off valueBack to article page