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Table 3 STRING analysis of Molecular Function of Gene Symbol distributions from the TRYP and TRYP STYP where delta and χ2 were both greater than 9 after correction

From: The plasma peptides of breast versus ovarian cancer

#Term IDTerm descriptionObserved gene countBackground gene countFalse discovery rate
GO:0005488Binding1152118789.77E−20
GO:0005515Protein binding69466053.83E−13
GO:0005524ATP binding20914621.30E−11
GO:0043167Ion binding63760661.30E−11
GO:0032559Adenyl ribonucleotide binding21315141.80E−11
GO:0008144Drug binding22717103.62E−10
GO:0035639Purine ribonucleoside triphosphate binding23217941.81E−09
GO:0032553Ribonucleotide binding23818683.13E−09
GO:0032555Purine ribonucleotide binding23618533.33E−09
GO:0097159Organic cyclic compound binding56053823.33E−09
GO:1901363Heterocyclic compound binding55253054.36E−09
GO:0097367Carbohydrate derivative binding26521634.89E−09
GO:0000166Nucleotide binding25820975.95E−09
GO:0008092Cytoskeletal protein binding1308825.00E−08
GO:0003779Actin binding764136.27E−08
GO:0043168Anion binding30926966.27E−08
GO:0016887ATPase activity733927.90E−08
GO:0036094Small molecule binding28224603.63E−07
GO:0042623ATPase activity, coupled603201.76E−06
GO:0017111Nucleoside-triphosphatase activity1117783.30E−06
GO:0004386Helicase activity361474.31E−06
GO:0016462Pyrophosphatase activity1148196.34E−06
GO:0046872Metal ion binding42040876.91E−06
GO:0043169Cation binding42541701.22E−05
GO:0003777Microtubule motor activity291101.74E−05
GO:0008017Microtubule binding482532.25E−05
GO:0051015Actin filament binding351583.76E−05
GO:0019899Enzyme binding24121979.02E−05
GO:0003774Motor activity301310.00012
GO:0015631Tubulin binding553440.00032
GO:0051020GTPase binding836140.00064
GO:0017048Rho GTPase binding321620.00073
GO:0003682Chromatin binding695010.0018
GO:0005089Rho guanyl-nucleotide exchange factor activity19760.0025
GO:0003676Nucleic acid binding33033320.0028
GO:0005198Structural molecule activity866790.0032
GO:0031267Small GTPase binding705250.0036
GO:0004672Protein kinase activity816350.0039
GO:0140096Catalytic activity, acting on a protein22521760.005
GO:0019904Protein domain specific binding877060.0061
GO:0005085Guanyl-nucleotide exchange factor activity463110.0066
GO:0005509Calcium ion binding867000.007
GO:0017016Ras GTPase binding665100.0103
GO:0005516Calmodulin binding321940.0106
GO:0004674Protein serine/threonine kinase activity594440.011
GO:0051010Microtubule plus-end binding7130.0119
GO:0005088Ras guanyl-nucleotide exchange factor activity372430.0143
GO:0005096GTPase activator activity402780.023
GO:0004004ATP-dependent RNA helicase activity15660.0237
GO:0016773Phosphotransferase activity, alcohol group as acceptor897670.0237
GO:0030695GTPase regulator activity433070.0237
GO:0060589Nucleoside-triphosphatase regulator activity473450.0237
GO:0044877Protein-containing complex binding1089680.0241
GO:0016772Transferase activity, transferring phosphorus-containing groups1099820.0255
GO:0032947Protein-containing complex scaffold activity15680.0267
GO:0008047Enzyme activator activity635100.0303
GO:0097493Structural molecule activity conferring elasticity7170.0325
GO:0016301Kinase activity948350.0352
GO:0051959Dynein light intermediate chain binding9290.0352
GO:0042800Histone methyltransferase activity (H3-K4 specific)580.0388
GO:0008094DNA-dependent ATPase activity14660.0482
GO:0140030Modification-dependent protein binding221310.0482
GO:0008026ATP-dependent helicase activity17900.0499
  1. Additional details see Table 2