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TableĀ 1 Biological processes classification of differential identified proteins in MSCs

From: Effects of cryopreservation and long-term culture on biological characteristics and proteomic profiles of human umbilical cord-derived mesenchymal stem cells

Biological processes Gene name
Differentiation GATA6, DKK1, STC1, PDGFRB, COL5A2, FST, CCNB1, AURKA, TOP2A, INHBA, COL1A1, ANLN, JUN, SEMA7A, NCAM1, COL12A1, NRP2, FBN2, HGF
Immune system regulation process TNFAIP3, KIF2C, PTX3, TMBIM1, IGHG1, JUN, NDRG1, NCAM1, MYO10, KIF22, COL1A1, RACGAP1, SEMA7A, KIF11, INHBA, MT2A, FST, C3, GEM, TOP2A, SERPINE1, KIF23, ANLN, PDCD1LG2, CRISPLD2, JUN
Wound healing and regeneration TNFAIP3, SERPINB2, GATA6, MKI67, SERPINE1, F3, FOSL1, AURKA, COL1A1, DCN, NRP2, HGF, JUN, C3, PDGFRB, CCNB1, TFPI2, HIST2H3A, CCNA2
Apoptotic signaling pathway BIRC5, STK17B, F3, TNFAIP3, SERPINE1, INHBA, TMBIM1, TIMP3, TOP2A, CHEK1, HGF, PDGFRB, TPX2, GATA6, SERPINB2, AURKA, CCNB1, TNFAIP3, NUAK1, FOSL1, AURKB, CPEB4, PLK1, JUN, ARAF, AMIGO2
Myeloid cell differentiation and ossification INHBA, FBN2, STC1, COL5A2, JUN, HGF, COL1A1, SEMA7A
Oxidation resistance TNFAIP3, PTX3, NDRG1, TIMP3, SERPINE1, COL1A1, NDRG1, STK17B,AURKA, PLK1, PDGFRB, CPEB4, AURKB, AMIGO2, TMBIM1, JUN, STC1, ARAF, GATA6, HGF, FOSL1, CCNB1, TOP2A, F3, CPEB4, BIRC5, SERPINB2, INHBA, CCNA2
Adaptive immune response TNFAIP3, IGHG1, MYO10, DCN, C3, HGF, PDCD1LG2, JUN, SEMA7A, FST, INHBA, PTX3, TOP2A, SERPINE1, NCAM1, ANLN, MT2A
Inflammatory response TNFAIP3, PTX3, SERPINE1, PDCD1LG2, SEMA7A, F3, HGF, C3
Interferon-gamma-mediated signaling pathway PDCD1LG2, NCAM1, INHBA, MT2A
Cartilage development STC1, BNC2, LUM, COL1A1, STC1, COL1A1, MEX3C
Regulation of cytokine production GATA6, LUM, TNFAIP3, SERPINE1, PDCD1LG2, SEMA7A, INHBA, HGF, C3
Angiogenesis SERPINE1, GATA6, PDGFRB, F3, JUN, HGF, NRP2, C3
Antigen processing and presentation RACGAP1, TNFAIP3, CCNA2, KIF22, INHBA, KIF11, KIF2C, KIF23
Cell migration F3, STC1, SERPINE1, SMURF2, DCN, COL1A1, PDGFRB, HGF, NRP2, JUN
Transforming growth factor beta1 production GATA6, COL1A1, C3, LUM, JUN, SERPINE1, TNFAIP3, PDCD1LG2, SEMA7A, HGF, INHBA
Response to growth factor PDGFRB, GATA6, NRP2, DKK1, SHCBP1, SHCBP1, CCNA2, SMURF2, COL1A1, SMURF2, JUN, FBN2, HGF, DCN, LUM
Aging CHEK1, SERPINE1, AURKB, PDGFRB, DCN, JUN
Regulation of endothelial cell proliferation SERPINE1, GATA6, DCN, TNFAIP3, THBS2, HGF, F3, C3, JUN, NRP2