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Table 5 Resources for studying the effect of mutations on kinases and phosphorylation sites

From: Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources

Tool

Last update

Version

Prediction type

Method

Kinases

Method of access

References

PhosSNP

2009

1.0

SNVs that might influence phosphorylation status

Rules

 

Tool

[89]

MIMP

2015

 

Missense SNV impact on kinase-substrate

Bayesian model

322

Web|DL|Tool

[91]

ReKINect

2015

 

Effect of SNV on signaling network

PSSM

 

Web|DL

[92]

PhosphoPICK-SNP

2016

 

Effect of SNV on phosphorylation level

Bayesian models

107

Web|DL

[93]

ActiveDriverDB

2017

 

Somatic variants affecting phosphorylation

Rules

322

Web|DL

[90]

  1. SNV single nucleotide variation, PSSM position specific scoring matrix