Fig. 5
From: Early changes in tear film protein profiles after femtosecond LASIK surgery
The amount of correction, flap thickness and flap diameter affect the protein expression levels. a–c Retinoic acid receptor responder protein 1 (RARRES1), protein disulfide-isomerase A4 (PDIA4), and apolipoprotein B-100 (APOB) expression level changes between Vpost and V1m time points correlated negatively with the amount of correction. d Flap thickness correlated positively with type II cytoskeletal 6A keratin (KRT6A) expression level changes between Vpre and V1m. e, f V1m expression levels of PDIA4 had a negative correlation and phosphatidylethanolamine-binding protein 1 (PEBP1) a positive correlation against the correction amount. g, h Flap diameter of 9.4 mm or over was associated with a decrease in expression levels of polymeric immunoglobulin receptor (PIGR) and immunoglobulin heavy variable 3–23 (IGHV3-23) 1 month after the surgery