Clinical Proteomics

Table 1 Overview of patient and tumor characteristics

From: Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

Patient	Time-points (min)	Gender	Age	Location	Tumor type	differentiation	Tumor % Peptide array	Tumor % LC–MS–MS
1	0	Male	62	Caecum	Adenocarcinoma	Good/intermediate	50%	50%
	30						80%
	60						95%	70%
	90						95%
	120						60%	70%
	150						80%
	180						70%	70%
2	0	Male	60	Rectum	Mucinous		20%
	30						7.5%
	60						5%
	90						10%
	120						10%
	150						20%
	180						20%
3	0	Male	74	Sigmoid	Adenocarcinoma	Good/intermediate	50%
	30						25%
	60						25%
	90						25%
	120						25%
	150						25%
	180						37.5%
4	0	Female	49	Caecum	Adenocarcinoma	Good/intermediate	75%	70%
	30						50%
	60						40%	55%
	90						30%
	120						20%	25%
	150						70%
	180						70%	35%
5	0	Male	64	Ascending colon	Adenocarcinoma	Good/intermediate	25%	30%
	30						50%
	60						50%	60%
	90						50%
	120						50%	40%
	150						50%
	180						50%	40%

Patient (1–5) and tumor characteristics of timepoint 0 and 6 timepoints between 30–180 min of CIT are listed, including tumor percentage (%) of each of the analyzed samples for both the kinase peptide array and with nano liquid chromatography-tandem mass spectrometry-based phospoproteomics (LC–MS–MS)

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ISSN: 1559-0275

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