Quantitative proteomics-based analyses performed on pre-eclampsia samples in the 2004–2020 period: a systematic review

Table 3 Full list of the 16 proteins whose expression patterns change consistently when comparing pre-eclamptic versus control urine samples

Accesion^a	Gene name^a	Protein name^a	PE > C^b,d	PE < C^c,d
P00450	CP	Ceruloplasmin	[91,92,93]
P00747	PLG	Plasminogen	[93, 94]
P01009	SERPINA1	Alpha-1-antitrypsin	[91,92,93,94,95,96,97]
P01024	C3	Complement C3	[91, 93]
P01042	KNG1	Kininogen-1		[92, 93]
P02452	COL1A1	Collagen alpha-1(I) chain	[96, 98]
P02461	COL3A1	Collagen alpha-1(III) chain	[96, 98]
P02768	ALB	Albumin	[92, 93, 96, 97]
P02787	TF	Serotransferrin	[93, 94]
P05154	SERPINA5	Plasma serine protease inhibitor		[93, 94]
P06396	GSN	Gelsolin		[92, 93]
P07911	UMOD	Uromodulin	[96, 98]
P41222	PTGDS	Prostaglandin-H2 D-isomerase		[92, 93]
P68871	HBB	Hemoglobin subunit beta	[93, 96]
P98160	HSPG2	Basement membrane specific eparin sulfate proteoglycan core protein		[92, 93]
Q12907	LMAN2	Vesicular integral-membrane protein VIP36		[92, 93]

^aAccording to UniprotKB
^bPE > C: expression levels have been described to be higher in pre-eclampsia versus control samples
^cPE < C: expression levels have been described to be lower in pre-eclampsia versus control samples
^dNumbers correspond to bibliographic references.
Reference 92 reports two independent data for KNG1, CP, SERPINA1, ALB, GSN, PTGDS, HSPG2 and LMAN2; reference 96 reports two independent data for SERPINA1, COL1A1, COL3A1, ALB, UMOD and HBB.

ISSN: 1559-0275