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Fig. 6 | Clinical Proteomics

Fig. 6

From: O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature

Fig. 6

OGA inhibition increases p62 levels and reduces radioresistance in GBM. a Interactome of proteins related to p62 protein (IGFBP3, HSPA5/GRP78/Bip, Rab7a, SQSMT1, PSMB4, PSMB2, PSMB4 and PSMC6). b Western blotting and quantification analysis of p62 levels. c Upon 72 h of treatment control and iOGA cells were irradiated with 10 Gy and viable cells were analyzed by Neubauer count along the following 72 h post irradiation. N = 3; * p < 0.05; *** p < 0.001; ns = not significant

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Clinical Proteomics

ISSN: 1559-0275