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Table 2 Candidate kidney-derived proteins and their efflux:influx expression ratios in seven individuals

From: Identification of biomarkers of chronic kidney disease among kidney-derived proteins

Protein

Donor no.

1

2

3

4

5

6

7

Average

Complement C1q subcomponent subunit A

3.35

4.48

4.60

9.16

3.22

2.56

38.66

9.43

Complement C1q subcomponent subunit B

6.35

12.27

0.58

21.21

5.72

2.75

14.47

9.05

Complement C1q subcomponent subunit C

7.78

10.61

4.28

17.80

6.12

2.80

7.32

8.10

Apolipoprotein(a)

2.23

13.08

1.08

2.79

4.83

2.99

16.42

6.20

Protein Z-dependent protease inhibitor

0.05

1.83

1.79

2.00

9.45

1.41

22.67

5.60

Corticosteroid-binding globulin

2.30

2.27

2.28

3.38

4.32

2.14

15.1

4.54

Lysosome-associated membrane glycoprotein 1

2.46

4.67

13.46

1.81

1.99

4.13

2.62

4.45

Phosphatidylinositol-glycan-specific phospholipase D

2.56

7.67

7.88

6.24

1.28

1.36

2.63

4.23

Plasma serine protease inhibitor

1.91

6.60

7.36

5.81

2.14

3.46

000

3.90

Apolipoprotein C-IV

4.69

8.70

2.15

4.60

0.77

1.47

3.02

3.63

  1. The efflux:influx ratio of each protein identified by LC–MS/MS was calculated for each individual
  2. The top 10 candidate proteins, whose efflux:influx ratio exceeded 1.5 in at least five individuals and exceeded 3.0 in at least two individuals, are indicated