Fig. 4

Box plots show examples of SOMAscan data for 6 differentially abundant proteins; a Alpha-1-antitrypsin (SERPINA1), b Interleukin-1 Receptor accessory protein (IL1RAP), c CC motif chemokine 18 (CCL18), d Complement component C1q receptor (CD93), e Immunoglobulin M (IgM), in non-asthma (NA), asthma without (A) and with small airway involvement (A-hLCI), and f Soluble Receptor of Advanced Glycation End products (sRAGE) in never-smokers (NS) and ex-smokers (ExS). Y-axis show normalized abundance (log2 transformation and normalization to mean 0 and variance 1). Box ranges from the 25th to the 75th percentile and median value is marked with dotted line. p values and false discovery rate adjusted p values (q) from various pairwise comparisons are shown over each box plot. Protein abundance data was adjusted for difference in age