Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls

Table 5 Proteins differentially expressed upon T cell activation are enriched for proteins expressed by MS-susceptibility genes

	Proteins not expressed by MS susceptibility genes	Proteins expressed by MS susceptibility genes
Not differentially expressed upon T cell activation^a	3849	54
Differentially expressed upon T cell activation^a	1758	43
Pearson Chi-squared test p-value		0.0089

In the two-by-two table, the annotated and quantified proteins in our data set are divided into proteins encoded by MS susceptibility genes or not. Statistical testing of significance was performed according to Pearson’s Chi-squared test, and the p-value is given in the table
^aProteins with Benjamini - Hochberg adjusted p - values ≤ 0.01 in the differential expression analysis between unstimulated and stimulated samples

ISSN: 1559-0275