From: Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates
Gene
Number of sites mutated
Total mutations
Shared mutations between tissue and matched primary cell line
APC
12
41
26
TP53
7
10
5
KRAS
2
4
BRAF
MSH2
3
MSH6
11
20
MLH1
8
PIK3CA
FBXW7