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Table 1 Mutations to CA-related genes in FFPE CA tissues and CA-derived primary cell lines

From: Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates

Gene

Number of sites mutated

Total mutations

Shared mutations between tissue and matched primary cell line

APC

12

41

26

TP53

7

10

5

KRAS

2

7

4

BRAF

2

4

4

MSH2

2

3

3

MSH6

11

26

20

MLH1

3

8

7

PIK3CA

4

11

5

FBXW7

2

2

2