Table 2 Pathological characteristics of patients with membranous nephropathy included in this study

Median time from presentation to biopsy (months) (range)

2 (1‒4)

2 (1‒24)

2 (1‒3)

Median percentage of global sclerotic glomeruli (range)

13 (4‒23)

4 (0‒6)

6 (0‒20)

TA (absent, mild, moderate, severe), n

1, 5, 0, 0

1, 5, 0, 0

2, 4, 0, 0

IFib (absent, mild, moderate, severe), n

0, 6, 0, 0

0, 5, 1, 0

1, 3, 2, 0

Glomerular IgG deposition (IF intensities), n

4 (2+), 2 (3+)

2 (+), 2 (2+), 2 (3+)

2 (+), 1 (2+), 3 (3+)

IgG1 (IF intensities), n

5 (−), 1 (±)

6 (−)

1 (±), 3 (+), 2 (2+)

IgG2 (IF intensities), n

3 (−), 2 (+), 1 (2+)

1 (−), 1 (±), 3 (+), 1 (2+)

2 (+), 2 (2+), 2 (3+)

IgG3 (IF intensities), n

4 (−), 2 (+)

5 (−), 1 (+)

5 (−), 1 (+)

IgG4 (IF intensities), n

2 (+), 1 (2+), 3 (3+)

2 (−), 1 (+), 3 (2+)

3 (−), 1 (±), 2 (+)

Glomerular IgA deposition (IF intensities), n

3 (−), 1 (±), 1 (+), 1 (2 +)

1 (−), 2 (±), 2 (+), 1 (2+)

2 (−), 2 (+), 2 (2+)

Glomerular IgM deposition (IF intensities), n

5 (−), 1 (+)

2 (−), 3 (±), 1 (+)

1 (−), 2 (±), 2 (+), 1 (2+)

Glomerular κ deposition (IF intensities), n

2 (+), 2 (2+), 2 (3+)

1 ( ±), 1 (+), 3 (2+), 1 (3+)

1 ( ±), 2 (+), 1 (2+), 2 (3+)

Glomerular λ deposition (IF intensities), n

2 (+), 2 (2+), 2 (3+)

1 ( ±), 1 (+), 3 (2+), 1 (3+)

2 (+), 2 (2+), 2 (3+)

Glomerular C3 deposition (IF intensities), n

4 (+), 2 (2+)

1 (−), 1 ( ±), 4 (+)

3 ( ±), 2 (+), 1 (3+)

Glomerular C1q deposition (IF intensities), n

6 (−)

5 (−), 1 ( ±)

3 (‒), 2 (+), 1 (2+)

MN stage on electron microscopy (I–IV), n

2 (I), 3 (II), 1 (NA)

2 (I), 1 (II), 1 (IV), 2 (NA)

4 (I), 1 (II), 1 (III)