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Table 1 Demographic, clinical characteristics and laboratory findings of SFTS patients

From: Serum proteomics of severe fever with thrombocytopenia syndrome patients

Characteristics

Recovered (n = 8)

Deceased (n = 3)

p-value

Epidemiology, no. (%)

   

 Age, mean Y ± SD (range)

71.0 ± 12.4

69.3 ± 11.02

0.8429

Female

4 (50.0)

2 (66.7)

0.9103

 Occupational exposure

3 (37.5)

1 (33.3)

0.6618

Comorbidities, no. (%)

   

 Cardiovascular disease*

1 (12.5)

0

0.5683

 Cerebrovascular disease

1 (12.5)

0

0.5683

 Pulmonary disease**

0

0

 Chronic kidney disease

0

0

 Diabetes mellitus

1 (12.5)

0

0.5683

 Malignancies

0

0

Clinical signs and symptoms, no. (%)

   

 Headache

2 (25.0)

1 (33.3)

0.8075

 Dyspepsia

5 (62.5)

2 (66.7)

0.9103

 Nausea/vomiting

5 (62.5)

1 (33.3)

0.4385

 Abdominal pain

5 (62.5)

0

0.0738

 Chills

6 (75.0)

3 (100)

0.3893

 Myalgia

5 (62.5)

2 (66.7)

0.9103

 Fatigue

7 (87.5)

1 (33.3)

0.4761

 Rash/Eschar

3 (37.5)

1 (33.3)

0.9103

 Tick bite

6 (75.0)

1 (33.3)

0.2413

Laboratory values, median (IQR)

   

 WBC count, × 1000/mm3

2276.3 (1150–4150)

1866.7 (1240–2400)

0.5659

 Platelet count, × 1000/mm3

57,125 (25,000–93,000)

33,000 (21,000–45,000)

0.1286

 aPTT, sec

40.9 (33.6–52.4)

84.4 (78.5–90.9)

 < 0.001

 Total bilirubin, mg/dL

1.5 (0.58–5.13)

2 (1.08–2.5)

0.5740

 Albumin, g/dL

3.2 (2.8–3.5)

2.5 (1.9–2.9)

 < 0.001

 AST, IU/L

337.4 (71–1210)

6670.7 (4710–9956)

 < 0.001

 ALT, IU/L

121.8 (46–242)

1096.3 (846–1366)

 < 0.001

 LD, IU/L

1562.6 (775–3082)

16,619.7 (14,915–18,030)

 < 0.001

 Creatinine, mg/dL

0.9 (0.44–1.28)

2.4 (2.22–2.8)

 < 0.001

 hs-CRP, mg/dL

9.5 (1.15–22.4)

34 (32.33–36.31)

 < 0.001

Ct value

   

 S segment

31.1 (23.56–36.88)

25.4 (21.16–31.5)

0.0805

 M segment

30.1 (22.26–33.65)

26.8 (22.26–33)

0.2839

  1. SFTS severe fever with thrombocytopenia syndrome; SD standard deviation; IQR, interquartile range; WBC white blood cell; aPTT activated partial thromboplastin time; AST aspartate aminotransferase; ALT alanine aminotransferase; LD lactate dehydrogenase; CRP C-reactive protein
  2. *Includes myocardial infarction, congestive heart failure, and peripheral vascular disease
  3. **Chronic obstructive pulmonary disease, asthma
  4. Statistically significant values are shown in bold