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Fig. 3 | Clinical Proteomics

Fig. 3

From: Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues

Fig. 3

Fermitin Family Member 2 (FERMT2) correlates with an increased risk of progression and is significantly elevated in HGSOC patients with high (> 1.1 cm) residual disease burden. A Kaplan–Meier curve illustrating the relationship between FERMT2 protein abundance and progression free survival (PFS) identified from a publicly available global proteomics data set of 154 HGSOC patient tissues (CPTAC Ovarian, 2016); high and low reflects median cut-point of FERMT2 protein abundance and Log-rank P reflects categorized, univariate log-rank testing. B FERMT2 protein abundance for patients exhibiting > 1.0 cm (> R1, n = 50), 0.1–1.0 cm (R1, n = 64) or no residual disease (R0, n = 24); * reflects Mann Whitney U P-value = 0.02

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