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Table 2 Top pathways activated or inhibited in post versus pre-NACT treated tumors

From: Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues

Diseases or functions annotation

Post versus Pre-NACTa (Activation z-score)

Synthesis of lipid

2.586

Cell survival

2.327

Cell viability

1.926

Phagocytosis of cells

1.671

Synthesis of fatty acid

1.534

Quantity of hydrogen peroxide

− 1.982

Inflammation of absolute anatomical region

− 2.023

Extracranial solid tumor

− 2.09

Inflammation of organ

− 2.118

Inflammation of body cavity

− 2.701

  1. aPositive values represent activation in post-NACT ovarian cancer tissue specimens and negative values represent activation in pre-NACT ovarian cancer tissue specimens
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Clinical Proteomics

ISSN: 1559-0275