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Fig. 3 | Clinical Proteomics

Fig. 3

From: Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation

Fig. 3

Left panels: GO-based enrichment analysis of DEPs between HD and COVID-19 non-ICU (A), HD and COVID-19 ICU/F (C), COVID-19 non-ICU and COVID-19 ICU/F (E) shown in the term of biological processes (two-sided hypergeometric test; p < 0.001) and the number of counts (n > 10). Redundant GO terms and those not relevant for plasma proteins were omitted (see Additional file 5: Table S5 for the full list). GO terms were sorted by P-Value. Right panels: Networks analysis of plasma proteins whose levels changed between HD and COVID-19 non-ICU patients (B) HD and COVID-19 ICU/F (D), COVID-19 non-ICU and COVID-19 ICU/F (F). The colors of the circles indicate the processes in which these proteins play a role as described in ACand E. Edges transparency is based on STRINGdb score

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Clinical Proteomics

ISSN: 1559-0275