Fig. 1

TMT proteomic analysis of follicular fluid samples achieved from RSA and Control group. A Volcano plot of the differentially expressed proteins. Blue and Red dots indicate low and high expression level proteins respectively. B Heatmap of normalized expression levels of differentially expressed proteins detected from RSA patients (RSA-1, RSA-2, RSA-3) and control group patients (CON-1, CON-2, CON-3). Blue and Red block indicate low and high expression levels respectively. C The top 20 enriched GO term: The abscissa in the graph show enrichment to GO function classification and the ordinate represents the number of different proteins under each functional classification; The significance of GO enrichment was calculated by Fisher’s exact test. The p value was indicated by the color of the bar. The numbers on the top of the bar represent the rich factor. D Enriched KEGG pathways: The abscissa in the graph represents the number of differentially expressed protein of each KEGG pathways. The significance of KEGG enrichment was calculated by Fisher’s exact test. The p value was indicated by the color of the bar