Table 1 Clinical parameters of CP patients without stones, CP patients with protein plugs and patients with calcified chronic pancreatitis

Age (years)

36 ± 15 (n = 900)

34 ± 14 (n = 246)

35.7 ± 12.99 (n = 1678)

0.254032571

Gender

 Male

728 (80.89%)

192 (78.05%)

1125 (67%)

 < 0.0001

 Female

172 (19.11%)

54 (21.95%)

553 (33%)

 < 0.0001

Complete blood picture (CBP)

 Haemoglobin (gm/dL)

12.6 ± 6.5 (n = 460)

12.8 ± 1.9 (n = 177)

12.6 ± 2.05 (n = 734)

0.832539986

 Total WBC (cells/mm³)

8808.2 ± 4791.4 (n = 460)

8906.8 ± 7655.9 (n = 177)

8105.7 ± 2741.71 (n = 734)

0.003318517

 Neutrophils (%)

65.7 ± 11.3 (n = 460)

63.5 ± 10.6(n = 177)

62.7 ± 10.14 (n = 734)

4.68E-09

 Lymphocytes (%)

25.9 ± 10.4 (n = 460)

28.2 ± 9.5 (n = 177)

28.8 ± 9.28 (n = 734)

2.37227E-10

 Eosinophils (%)

3.1 ± 2.8 (n = 460)

3.3 ± 2.8 (n = 177)

3.2 ± 2.53 (n = 734)

0.469180491

 Monocytes (%)

5.3 ± 2.9 (n = 460)

5.0 ± 1.8 (n = 177)

5.3 ± 3.1 (n = 734)

0.160235454

 Platelet count (lakhs/mm³)

2.6 ± 1.5 (n = 460)

2.5 ± 0.9 (n = 177)

2.4 ± 0.93 (n = 734)

0.00644478

Renal function test

 Blood urea (mg/dL)

28.2 ± 18.9 (n = 234)

26.5 ± 23.4 (n = 115)

22.9 ± 11.24 (n = 502)

1.21441E-06

 Creatinine (mg/dL)

1 ± 0.6 (n = 234)

0.99 ± 0.71 (n = 115)

0.95 ± 1.04 (n = 501)

0.1155404

Liver function test

 Total Bilirubin (mg/dL)

1.2 ± 1.8 (n = 470)

1.01 ± 1.01 (n = 179)

1.2 ± 3.73 (n = 742)

0.291647286

 SGPT (ALT) (U/L)

43 ± 63.2 (n = 470)

45.82 ± 66.60(n = 179)

35.4 ± 39.88 (n = 742)

0.003183362

 SGOT (AST) (U/L)

38.2 ± 50.9 (n = 470)

40.51 ± 62.7 (n = 179)

32.8 ± 28.62 (n = 742)

0.011630782

 ALP (U/L)

151.5 ± 182.3 (n = 470)

148.7 ± 152.6 (n = 179)

126.9 ± 117.52(n = 742)

0.002823298

 Total proteins (gm/dL)

7.8 ± 5.2 (n = 470)

7.8 ± 4.4 (n = 179)

7.5 ± 0.74 (n = 742)

0.26545353

 Albumin (gm/dL)

4.3 ± 1.3 (n = 470)

4.3 ± 0.6 (n = 179)

4.2 ± 0.58 (n = 742)

0.355579422

 Globulin (gm/dL)

3.2 ± 1.4 (n = 470)

3.2 ± 0.5 (n = 179)

3.3 ± 0.5 (n = 742)

0.449561731

Thyroid profile

 T3 (ng/mL)

1.2 ± 1.5 (n = 44)

1.0 ± 0.2 (n = 18)

1.0 ± 0.2 (n = 205)

0.061662891

 T4 (µg/dL)

10.3 ± 13.8 (n = 44)

8.1 ± 1.8 (n = 19)

7.8 ± 1.58 (n = 205)

0.031168078

 TSH (mIU/mL)

3.5 ± 7.4 (n = 98)

2.6 ± 1.5 (n = 32)

2.6 ± 2.87 (n = 254)

0.02533354

Lipid profile

 Total Cholesterol (mg/dL)

180.3 ± 48.3 (n = 138)

179.3 ± 41.8 (n = 38)

182.9 ± 44.89 (n = 143)

0.84439935

 HDL Cholesterol (mg/dL)

37.3 ± 8.9 (n = 138)

39.8 ± 9.1 (n = 38)

41.7 ± 13.22 (n = 143)

0.002427905

 VLDL Cholesterol (mg/dL)

32.4 ± 16.3 (n = 138)

29.2 ± 15.0 (n = 38)

31.1 ± 17.79 (n = 143)

0.487241088

 Direct LDL Cholesterol (mg/dl)

109 ± 42 (n = 138)

111.1 ± 32.9 (n = 38)

112.7 ± 41.91 (n = 143)

0.734537519

 Triglycerides (mg/dL)

166.7 ± 95.9 (n = 138)

146.4 ± 74.3 (n = 38)

153.2 ± 79.85 (n = 155)

0.19558935

 Serum Amylase (U/L)

229.4 ± 383.5 (n = 179)

361.1 ± 2027.9 (n = 81)

112.8 ± 232.93

(n = 273)

0.027901594

 Lipase (U/L)

237 ± 666 (n = 322)

246.8 ± 907.6 (n = 126)

89.1 ± 252.06 (n = 398)

0.000378482

 Fasting blood glucose (mg/dL)

125.8 ± 60.1 (n = 334)

135.4 ± 94.5 (n = 133)

137.7 ± 71.1 (n = 476)

0.011276096

 Random blood glucose (mg/dL)

161.9 ± 97.7 (n = 207)

156.1 ± 109.2 (n = 88)

154.9 ± 89.54 (n = 444)

0.566125234

 C-peptide (ng/mL)

2.6 ± 2.2 (n = 67)

2.5 ± 2.3 (n = 43)

2.1 ± 2.14 (n = 125)

0.173942407

 Erythrocyte sedimentation rate (ESR) (mm/Hr)

30.7 ± 72.7 (n = 255)

24.7 ± 22.1 (n = 99)

27.9 ± 23.35 (n = 474)

0.128745055

 Parathyroid hormone (PTH) (pg/mL)

54.9 ± 34.2 (n = 73)

52.7 ± 24.1 (n = 29)

55.4 ± 49.35 (n = 90)

0.940386898

 HBA1C %

7.3 ± 2.6 (n = 365)

7.5 ± 2.4 (n = 138)

7.5 ± 2.32 (n = 573)

0.486795981

 Vit D (ng/mL)

22.4 ± 21.2 (n = 184)

18.8 ± 10.1 (n = 82)

19.5 ± 12.35 (n = 143)

0.039242099

 Vit B12 (pg/mL)

515.7 ± 436 (n = 195)

479.6 ± 432.7(n = 85)

546.6 ± 433.57 (n = 242)

0.365561035

 Serum creatinine (mg/dL)

1.01 ± 0.6 (n = 167)

0.9 ± 0.3 (n = 68)

0.96 ± 0.51 (n = 138)

0.214194904

 Calcium (mg/dL)

9.5 ± 1.1 (n = 116)

9.5 ± 0.9 (n = 32)

9.7 ± 0.77 (n = 102)

0.25693458

 RANSOD (U/mL)

233.3 ± 78.1 (n = 17)

977.7 ± 2386.5 (n = 10)

498.4 ± 1399.1(n = 29)

0.438912

 RANSEL (U/L)

8706.3 ± 1517.9

(n = 23)

8792 ± 3688 (n = 11)

8130.6 ± 2128.0 (n = 29)

0.585967

 Insulin fasting (MIU/L)

11.3 ± 16.1 (n = 15)

7.29 ± 6.55 (n = 9)

13 ± 34.8 (n = 35)

0.862915

Elastase (Stool) (µg/g)

51.8 ± 13.5 (n = 18)

59.5 ± 43.3 (n = 11)

45.2 ± 34.5 (n = 41)

0.400307