Table 1 Isogenic cellular models of FLT3 mutant AML analyzed by pHASED or single-shot LFQ protocols in biological triplicate (n = 9/technique, 18 total)
Cell line | Species | Biological replicates | Samples | Model of AML stage | Sorafenib sensitivity |
|---|---|---|---|---|---|
FDC-P1 | Mouse | 3 | FLT3-ITD | Diagnosis | Sensitive |
FDC-P1 | Mouse | 3 | FLT3-ITD/D835V | Relapse | Resistant |
FDC-P1 | Mouse | 3 | FLT3-ITD/D835Y | Relapse | Resistant |