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Fig. 4 | Clinical Proteomics

Fig. 4

From: LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy

Fig. 4

Multivariate data analysis of IgAN metabolomics data. A Principal Component (PC) scores plot from PLS-DA model. The diagonal shown the pairwise scoring plots between the five principal components with the corresponding variances. B OPLS-DA score plot showed the separation between the control group and IgAN. C Volcano plot of DEMs. The red points represented up-regulated metabolites, and the blue points characterized down-regulated metabolites in the IgAN group. D Heat map presenting DEMs between the IgAN and control groups. (Red represents up-regulated, and blue represents down-regulated in the IgAN group)

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