A proteomic profile of the healthy human placenta

Table 2 Summary of differentially expressed proteins (HGNC identifier) between maternal, middle, and fetal sub-anatomical regions

	Up DEP	Top 3 DEP	FC	Down DEP	Top 3 DEP	FC
Maternal vs middle sub-anatomical region	128	MYH11*** NUTF2* CFHR1***	1.48 1.01 0.80	152	PZP* SCIN* KDELC2***	− 1.41 − 1.15 − 0.79
Maternal vs fetal sub-anatomical region	115	MYH11* COL14A1* NUTF2**	1.24 1.16 1.00	123	KRT19* SNRPD2 CAPS*	− 0.71 − 0.69 − 0.52
Middle vs fetal	64	PZP* SCIN* LTF***	2.29 0.80 0.70	41	DES* SNRPD2 ERAP1***	− 0.74 − 0.66 − 0.46

Top three DEPs MYH11, NUTF2, CFHr1, COL14A1, NUTF2, PZP, SCIN, LFT based on highest fold change (FC). Adjusted p val < 0.05, up = upregulated, down = downregulated. *** = adjusted p val < 0.001, ** = adjusted p val < 0.01, * = adjusted p val < 0.05. p values adjusted for FDR

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