Fig. 3

Correlations between normalized plasma protein expression and sepsis patient parameters on ICU Day-1 and Day-3. Heat maps of rank-based classifying proteins reported in Fig. 1 on ICU Day-1 (A) and ICU Day-3 (B) are illustrated (y -axis) along with patient parameters (x-axis). Only proteins that showed a significant correlation (P < 0.05) with at least one biochemical or clinical parameter are illustrated. Significant correlations had a Pearson R-value of ≥ 0.5 or ≤ -0.5 and P < 0.05, denoted by *. Positive correlations are depicted in red and negative correlations in blue. MODS Multiple Organ Dysfunction Score, SOFA Sequential Organ Failure Assessment, P/F arterial partial pressure of oxygen divided by the fraction of inspired oxygen concentration, MV mechanical ventilation, Vaso vasopressors, HgB hemoglobin concentration, WBC white blood cell count, PMN neutrophil count; Lymph lymphocyte count, PLT platelet count, PTT partial thromboplastin time, INR international normalized ratio, Creat creatinine concentration