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Table 1 Basic characteristics of inflammatory bowel disease (IBD) and controls subjects (HC)

From: Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation

 

IBD

HC

Total (n = 38)

UC (n = 28)

CD (n = 10)

Total (n = 26)

HC_F (n = 13)

HC_NF (n = 13)

UC_F (n = 14)

UC_NF (n = 14)

CD_F (n = 5)

CD_NF (n = 5)

Age, Median (range)

43.0(18–71)

46.5(27–71)

44.0(22–62)

40.0(18–52)

30.0(27–53)

42.5(27–54)

45.0(27–53)

41.0(29–54)

Male, n (%)

22(31.8)

6(42.9)

9(64.3)

4(80.0)

3(60.0)

20(32.0)

12(92.3)

8(61.5)

BMI, Median (range)

24.36(16.16–33.22)

26.44(25.61–30.30)a

20.32(16.71–23.53)

27.28(25.18–33.22)b

18.37(16.16–19.59)

24.44(18.61–31.77)

25.38(25.00–31.77)c

21.36(18.61–23.88)

Duration of disease, Median year (range)

5.0 (3–7)

4.5 (3–7)

5.0 (4–7)

5.0 (3–5)

5.0 (4–6)

   

Disease extent: UC, n

 Proctitis

–

0

0

–

–

–

–

–

 Left-sided colitis

–

5

3

–

–

–

–

–

 Pancolitis

–

9

11

–

–

–

–

–

Disease extent: CD, n

 Ileal

–

–

–

1

2

–

–

–

 Colonic

–

–

–

1

1

–

–

–

 Ileocolonic

–

–

–

3

2

–

–

–

Current IBD medications, n

 5-ASA

-

14

14

0

0

–

–

–

 Corticosteroids

–

3

5

0

0

–

–

–

 Immunomodulators

–

0

0

2

1

–

–

–

 Biologics

–

0

0

5

5

–

–

–

  1. IBD inflammatory bowel disease, HC Controls, UC ulcerative colitis, CD Crohn’s disease, F with-overweight/obesity, NF without-overweight/obesity, BMI body mass index, HBI Harvey Bradshaw index, 5-ASA 5-aminosalicylic acid
  2. aP < 0.0001 indicates between UC_F and UC_NF
  3. bP = 0.0079 indicates between CD_F and CD_NF
  4. cP < 0.0001 indicates between HC_F and HC_NF