Fig. 6

Comparison of the effects of pre-and post-chemotherapy (Group 1: RN0 vs RN1 vs HC), pre-and post-surgery (Group 2: RN0 vs RS0 vs HC), and surgery plus chemotherapy (Group 3: RN0 vs RS0 vs RS1 vs HC) on the distribution of urine protein identified by DIA and PRM. RMS: rhabdomyosarcoma. HC healthy control, RN0 newly diagnosed RMS at the time points of admission, RN1 newly diagnosed RMS at the time points after 4 cycles of chemotherapy, RS0 RMS underwent surgery at the time points of admission, RS1 RMS underwent surgery at the time points after 4 cycles of chemotherapy, DIA data-independent acquisition, PRM parallel reaction monitoring analysis, DP differential proteins