Table 1 Characteristics of RMS and HC group in cohort 1 and cohort 2
From: Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children
Variables | Cohort 1 (N = 55) | Cohort 2 (N = 79) | ||||
|---|---|---|---|---|---|---|
RMS (N = 43) | HC (N = 12) | P | RMS (N = 54) | HC (N = 25) | P | |
Age (Months) | 41.00(22.00–70.00) | 57.00(38.25–78.25) | 0.89 | 54.5(25.38–98.00) | 53.00(25.00–81.00) | 0.62 |
Gender (M/F) | ||||||
 Male | 26(60.47) | 7(58.33) | 0.89 | 30(55.56) | 11(44.00) | 0.34 |
 Female | 17(59.53) | 5(41.67) | – | 24(44.44) | 14(56.00) | – |
LDH (U/L) | 307.00(261.5–394.00) | – | – | 306.50(246.50–373.75) | – | – |
Pathological type | ||||||
 ARMS | 18(41.86) | – | – | 28(51.85) | – | – |
 ERMS | 25(58.14) | – | – | 25(46.30) | – | – |
Sites of the primary tumor | ||||||
 Head and neck | 13(30.23) | – | – | 17(31.48) | – | – |
 Eye socket | 1(2.33) | – | – | 2(3.70) | – | – |
 Beside the meninges area | 12(27.91) | – | – | 14(25.93) | – | – |
 Limbs | 4(9.30) | – | – | 17(31.48) | – | – |
 Trunk | 3(6.98) | – | – | 6(11.11) | – | – |
 Abdominal pelvic | 6(13.95) | – | – | 6(11.11) | – | – |
Genitourinary system | 4(9.30) | – | – | 2(3.70) | – | – |
Tumor diameter | ||||||
  ≤ 5 cm | 24(43.56) | – | – | 32(59.26) | – | – |
 5-10 cm | 15(34.88) | – | – | 17(31.48) | – | – |
  ≥ 10 cm | 4(9.30) | – | – | 5(9.26) | – | – |
FOXO1 | ||||||
 Negative | 26(60.47) | – | – | 26(48.15) | – | – |
 Positive | 15(34.88) | – | – | 22(40.74) | – | – |
Risk assessment | ||||||
 Low-risk | 4(9.30) | – | – | 2(3.70) | – | – |
 Moderate-risk | 33(76.74) | – | – | 45(83.33) | – | – |
 High-risk | 3(6.98) | – | – | 3(5.56) | – | – |
 Central aggression | 3(6.98) | – | – | 4(7.41) | – | – |