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Fig. 4 | Clinical Proteomics

Fig. 4

From: Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands

Fig. 4

The Cytoscape visualisation of the STRING-generated network is composed of experimentally verified protein–protein interactions among the most common proteins identified in the CAL (A), LIP (B) and MIX (C) groups. The size of nodes corresponds with the frequency of occurrence of protein among all of the samples in the respectively groups; bigger nodes represent higher frequency, and smaller – ones represent lower frequency. The circles' colours correspond to Uniprot Annotated Keywords enrichment: green—secreted, orange—antimicrobial, blue—signal, pink—immunity, yellow—calcium. Fill colours correspond with Biological Process (GO) enrichment: yellow – defence response to the bacterium, blue – regulated exocytosis, green – neutrophil degranulation

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