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Fig. 6 | Clinical Proteomics

Fig. 6

From: Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands

Fig. 6

The Cytoscape visualisation of the STRING-generated network comprises experimentally verified protein–protein interactions among the most common proteins identified in (A) the CAL, (B) LIP and (C) the MIX group. The size of nodes corresponds with the frequency of occurrence of protein among all of the samples in the group; more significant nodes represent higher frequency, and smaller—ones represent lower frequency. The gradation of the fill corresponds with the median value of log2FC, presenting the type of regulation of protein: red—up-regulation of protein among the whole group and blue—down-regulation of protein. The darker the colour means, the more significant the difference. The green colour presents the case when the protein regulation level varies among the group's proteins. The yellow colour in the circles corresponds to the uniqueness of protein for the group

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Clinical Proteomics

ISSN: 1559-0275