Table 2 The list of proteins exhibited by log₂ fold change > 0.58 and < -0.58 (> 1.5-fold differential expression) in either non-metastatic or metastatic CRC patients compared to healthy controls.

P02750

LRG1

Leucine-rich α-2-glycoprotein (LRG)

7

0.34^*** (0.31 to 0.36)

0.95^**** (0.95 to 0.95)

P05109

S100A8

Protein S100-A8 (S10A8)

2

-0.12 (-0.17 to -0.08)

0.91^*** (0.84 to 0.98)

P0C0L4

C4A

Complement C4-A (CO4A)

2

0.87^*** (0.82 to 0.92)

0.88^*** (0.77 to 0.94)

P02748

C9

Complement component C9 (CO9)

14

0.20^** (0.17 to 0.23)

0.80^*** (0.77 to 0.84)

P0C0L5

C4B

Complement C4-B (CO4B)

2

0.56^** (0.50 to 0.62)

0.59^*** (0.52 to 0.69)

P02775

PPBP

Platelet basic protein (CXCL7)

4

0.63^*** (0.58 to 0.66)

0.58^** (0.53 to 0.65)

P14625

HSP90B1

Endoplasmin (ENPL)

2

1.51^**** (1.49 to 1.53)

-0.08 (-0.17 to 0.07)

P02747

C1QC

Complement C1q subcomponent subunit C (C1QC)

3

0.82^** (0.77 to 0.85)

-0.09 (-0.18 to -0.04)

P02751

FN1

Fibronectin (FN)

25

-0.67^** (-0.69 to -0.64)

-0.80^** (-0.82 to -0.79)

P02656

APOC3

Apolipoprotein C-III (APOC3)

2

-0.16^* (-0.18 to -0.15)

-0.87^*** (-0.91 to -0.81)

The elute fraction

P00738

HP

Haptoglobin (HP)

9

0.26^* (0.24 to 0.29)

0.84^**** (0.80 to 0.88)

P02763

ORM1

alpha-1-acid glycoprotein 1 (AGP1)

4

0.30^** (0.26 to 0.36)

0.68^**** (0.67 to 0.69)

P01009

SERPINA1

alpha-1-antitrypsin (A1AT)

11

0.47^** (0.41 to 0.52)

0.61^*** (0.60 to 0.64)

P68871

HBB

Hemoglobin subunit β (HBB)

6

0.68^*** (0.65 to 0.70)

0.58^** (0.56 to 0.59)

P01861

IGHG4

Immunoglobulin heavy constant γ4 (IGHG4)

3

-1.05^**** (-1.10 to -0.99)

-0.66^**** (-0.68 to -0.64)