Table 5 Validation of 10 diet-related proteins and lipoprotein outcomes in the Atherosclerosis Risk in Communities (ARIC) Studya
| Â | Â | Â | HDL-C (mmol/L) | Triglyceride (mmol/L) | non-HDL-C (mmol/L) | TC:HDL-C ratio | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Name of the protein | Uniprot ID | Entrezgene symbol | \(\beta\) | P-value | \(\beta\) | P-value | \(\beta\) | P-value | \(\beta\) | P-value |
Apolipoprotein M | O95445 | APOM | 0.11 | 1.09 × 10− 57 | — | — | — | — | — | — |
Afamin | P43652 | AFM | 0.002 | 7.92 × 10− 1 | — | — | — | — | — | — |
Collagen alpha-3(VI) chain | P12111 | COL6A3 | — | — | 0.13 | 2.65 × 10− 3 | -0.30 | 2.01 × 10− 11 | — | — |
Chitinase-3-like protein 1 | P36222 | CHI3L1 | — | — | 0.09 | 4.90 × 10− 35 | — | — | — | — |
Inhibin beta A chain | P08476 | INHBA | — | — | 0.69 | 2.20 × 10− 193 | — | — | — | — |
Palmitoleoyl-protein carboxylesterase NOTUM | Q6P988 | NOTUM | — | — | 0.09 | 1.44 × 10− 8 | — | — | — | — |
Cathelicidin antimicrobial peptide | P49913 | CAMP | — | — | 0.38 | 1.27 × 10− 137 | 0.29 | 1.74 × 10− 73 | — | — |
Guanylate-binding protein 2 | P32456 | GBP2 | — | — | — | — | — | — | 6.10 | 1.01 × 10− 46 |
COP9 signalosome complex subunit 7b | Q9H9Q2 | COPS7B | — | — | — | — | 0.15 | 4.39 × 10− 30 | — | — |
Sodium-coupled monocarboxylate transporter 1 | Q8N695 | SLC5A8 | -0.06 | 7.67 × 10− 36 | — | — | — | — | 4.48 | 7.03 × 10− 21 |