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Fig. 4 | Clinical Proteomics

Fig. 4

From: Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers

Fig. 4

Comparison of discriminatory power of the 5-marker panel versus the best single marker in primary glial cells. Five proteins were selected from t-test and ROC curve and used to construct the 5-marker panel, and its performance was evaluated. Logistic regression algorithms were used, in which enter method was used to evaluate the discriminatory power between control and grade 2, 4, 3 and 4 groups (Control: 10, Grade 2: 10, Grade 3: 12, and Grade 4: 15). The results of the evaluation between the best single marker A and C and 5-marker panel B and C are presented as confusion matrices with sensitivity, specificity, and error rate, and ROC curves D, E, and F are also represented by AUC values

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