Fig. 4

Sample clustering by average histology counts. A Percent neoplastic cells correlated with KRAS VAF for the surface H&E slide and B an average over 3 serial H&E slides. C Tumor clustering using percent cell types assessed by histology and averaged over multiple slides taken throughout the core. D Average percent acinar cells, E neoplastic cells, F desmoplastic stroma, and G fibrosis for the three histology clusters. *p < 0.005, **p < 0.0005