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Fig. 5 | Clinical Proteomics

Fig. 5

From: Frozen tissue coring and layered histological analysis improves cell type-specific proteogenomic characterization of pancreatic adenocarcinoma

Fig. 5

Proteomics differences in tumor vs stroma. A Proteomics abundance z score for proteins significantly different between the tumor and stroma clusters. B Protein abundance for four proteins that were identified as tumor-epithelial specific in the CPTAC PDAC study. C Protein abundance in tumor vs stroma clusters including proteins annotated as drug targets. D CEACAM1 protein abundance in the samples with a KRAS variant allele frequency increased > 20% in the epithelial-enriched core compared to the stroma-enriched core and bulk tissue. E CPOX protein abundance in the samples with a KRAS variant allele frequency increased > 20% in the epithelial-enriched core compared to the stroma-enriched core and bulk tissue

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