Fig. 4

A Comparison Group SENS and group NONE with Benjamin-Hochberg FDR corrected t-test p value (< 0.05) passing proteins. The horizontal axis is all 90 samples analyzed in the study and vertical axis listed all quantified 804 proteins. Dendrogram for samples is shown on top of the heatmap, and the NONE group in green squares and the SENS group in red squares. The dark blue to dark red color gradient denotes lower to higher expression. B Protein correlation of two selected cluster from heatmap significant enrichment. Co-regulated proteins labeled the same color. Red and blue colored proteins present positive and negative correlated with group separation, respectively.C Boxplot of highly regulated protein expression, C1QA and LGALS1 for up-regulated; APOC3 and DSG1 for down-regulated. SENS group colored in red, and NONE group colored in blue. D Scatter plot between up regulated proteins C1QA and LGALS1, and Down regulated proteins APOC3 and DSG1, respectively. Dots are values of protein expression with a shadow of 95% confident interval