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Fig. 5 | Clinical Proteomics

Fig. 5

From: Exploring the novel duo of Reticulocalbin, and Sideroflexin as future biomarker candidates for Exacerbated Chronic Obstructive Pulmonary Disease

Fig. 5

Receiver operator characteristic (ROC) curve of reticulocalbin-1, sideroflexin-4 and liprinα-3 in exacerbated COPD plasma samples: Classical ROC curve for single variable was constructed for the proteins RCN-1, SFXN-4 and LIPα-3 using Metaboanalyst 5.0. RCN-1 showed an area under the curve (AUC) value of 0.908, whereas SFXN-4 showed an AUC value of 0.715 with LIPα-3 showing an AUC value of 0.854. RCN1 and SFXN4 were upregulated in COPD exacerbation whereas LIPα-3 was downregulated in the disease with respect to healthy control, as depicted in the boxplot

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