Table 2 Correlation between the clinicopathologic features and immune subtypes in patients with breast cancer
From: Proteomic analysis of breast cancer based on immune subtypes
Factors | Immune subtypes | p-value | |
|---|---|---|---|
Inflamed (%) | Excluded/desert (%) | ||
Age | 0.039* | ||
< 50 | 21 (68) | 21 (91) | |
≥ 50 | 10 (32) | 2 (9) | |
Subtypes | 0.066 | ||
HR + HER2− | 7 (23) | 11 (48) | |
HR + HER2 + | 4 (13) | 2 (9) | |
HR-HER2 + | 2 (7) | 4 (17) | |
TNBC | 18 (58) | 6 (26) | |
Histologic types | 0.386 | ||
IBC-NST | 30 (97) | 21 (91) | |
ILC | 1 (3) | 2 (9) | |
Non-pCR/pCR | 0.055 | ||
Non-pCR | 18 (58) | 19 (83) | |
pCR | 13 (42) | 4 (17) | |
RCB class | 0.223 | ||
0 | 3 (10) | 2 (9) | |
I | 11 (36) | 14 (61) | |
II | 4 (13) | 3 (13) | |
III | 13 (42) | 4 (17) | |
Non-relapse/Relapse | 0.887 | ||
Non-relapse | 21 (68) | 16 (70) | |
Relapse | 10 (32) | 7 (30) | |
TILs (%) | < 0.001* | ||
< 10 | 0 | 23 (100) | |
10–19 | 12 (39) | 0 | |
≥ 20 | 19 (61) | 0 | |
TLS score | 0.45 | ||
0 | 15 (52) | 16 (70) | |
1 | 6 (21) | 4 (17) | |
2 | 3 (10) | 2 (9) | |
3 | 5 (17) | 1 (4) | |
Klintrup criteria | < 0.001* | ||
0 | 0 | 2 (9) | |
1 | 3 (10) | 14 (61) | |
2 | 16 (55) | 4 (17) | |
3 | 10 (35) | 3 (13) | |
Stroma (%) | 0.594 | ||
Low (< 50) | 13 (42) | 8 (35) | |
High (≥ 50) | 18 (58) | 15 (65) | |