Table 1 Characteristics of apolipoproteins across the lipoprotein classes
Apo | Lipoproteins | Exchangeable? | Site of synthesis |
|---|---|---|---|
ApoB100 | VLDL, IDL, LDL, Lp(a) | No | Liver |
ApoB48 | CM, CM remnants | No | Intestine |
Apo(a) | Lp(a) | No | Liver |
ApoA-I | HDL, CM | Yes | Liver, intestine |
ApoA-II | HDL, CM | Yes | Liver, intestine |
ApoA-IV | HDL, CM | Yes | Intestine |
ApoC-I | CM, VLDL, IDL, and HDL | Yes | Liver |
ApoC-II | CM, VLDL, IDL, and HDL | Yes | Liver, intestine, macrophages |
ApoC-III | CM, VLDL, IDL, and HDL | Yes | Liver |
ApoE | CM, CM remnants, VLDL, IDL, HDL | Yes | Liver, intestine, macrophages, brain |