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Table 3 GFAP, NFL and tau as exploratory multivariable predictors of αAQP4 and αMOG positivity

From: The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies

Autoantibodies

αAQP4

Markers

OR (95% CI)1

P-value2

Number of samples

Adjusted3 AUC

GFAP + NFL

GFAP

2.37 (1.37, 4.11)

0.002

20

0.77

NFL

0.87 (0.50, 1.51)

0.62

GFAP + tau

GFAP

2.56 (1.51, 4.31)

< 0.001

20

0.77

tau

0.69 (0.38, 1.27)

0.24

αMOG

tau + NFL

tau

0.38 (0.21, 0.67)

< 0.001

32

0.71

NFL

0.94 (0.62, 1.43)

0.78

tau + GFAP

tau

0.37 (0.21, 0.66)

< 0.001

32

0.71

GFAP

1.00 (0.63, 1.57)

0.99

  1. 1OR: Odds ratio; CI: confidence interval; AUC: area under the ROC curve
  2. 2P-value was calculated by multiple logistic regression
  3. 3Optimism-adjusted
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Clinical Proteomics

ISSN: 1559-0275