Ficarro SB, McCleland ML, Stukenberg PT, et al. Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisae. Nat Biotechnol 2002;19:01–305.
Google Scholar
Oda Y, Nagasu T, Chait BT. Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome. Nat Biotechnol 2001;19:379–382.
Article
PubMed
CAS
Google Scholar
Zhou H, Watts JD, Aebersold R. A systematic approach to the analysis of protein phosphorylation. Nat Biotechnol 2001;19:375–378.
Article
PubMed
CAS
Google Scholar
Yarden Y. The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. Eur J Cancer 2001;37:S3-S8.
Article
PubMed
CAS
Google Scholar
Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy Oncogene 2000;19:6550–6565.
Article
PubMed
CAS
Google Scholar
Voldborg BR, Damstrup L, Spang-Thomsen, M. & Poulsen H. S. Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann Oncol 1997;12:1197–1206.
Article
Google Scholar
Moscatello DK, Holgado-Madruga M, Godwin, AK, et al. Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors. Cancer Res 1995;55:5536–5539.
PubMed
CAS
Google Scholar
Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183–232.
Article
PubMed
CAS
Google Scholar
Scambia G, Benedetti-Panici P, Ferrandina G, et al. Epidermal growth factor, oestrogen and progesterone receptor expression in primary ovarian cancer: correlation with clinical outcome and response to chemotherapy. Br J Cancer 1995;72:361–366.
PubMed
CAS
Google Scholar
Simpson BJ, Phillips HA., Lessels AM, Langdon SP, Miller WR. c-erbB growth-factorreceptor proteins in ovarian tumours. Int J Cancer 1995;64:202–206.
Article
PubMed
CAS
Google Scholar
Slamon D. J., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1987;235:177–182.
Article
PubMed
CAS
Google Scholar
Herbst RS. ZD1839: targeting the epidermal growth factor receptor in cancer therapy. Expert Opin. Invest Drugs 2002;11:837–849.
Article
CAS
Google Scholar
Moyer JD, Barbacci EG, Iwata KK, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997;57:4838–4848.
PubMed
CAS
Google Scholar
Traxler P, Bold G, Buchdunger E, et al. Tyrosine kinase inhibitors: from rational design to clinical trials. Med Res Rev 2001;21,499–512.
Article
PubMed
CAS
Google Scholar
Caravatti G, Bruggen J, Buchdunger E, et al. Pyrrolo[2,3-d]Pyrimidine and Pyrazolo[3,4-d] Pyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase. ACS Symposium Series, ed. 796: Anticancer Agents. Oxford University Press, USA:2001;231–244.
Google Scholar
Bruns CJ, Solorzano CC, Harbison MT, et al. Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res 2000;60,2926–2935.
PubMed
CAS
Google Scholar
Brandt R, Wong AML, Hynes NE. Mammary glands reconstituted with Neu/ErbB2 transformed HC11 cells provide a novel orthotopic tumor model for testing anti-cancer agents. Oncogene 2001;20:5459–5465.
Article
PubMed
CAS
Google Scholar
Baker CH, Solorzano CC, Fidler IJ. Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer Res 2002;62:1996–2003.
PubMed
CAS
Google Scholar
Ferrari S, Bandi HR, Hofsteenge J, Bussian BM, Thomas G. Mitogen-activated 70K S6 kinase. Identification of in vitro 40 S ribosomal S6 phosphorylation sites. J Biol Chem 1991;266(33):22770–22775.
PubMed
CAS
Google Scholar
Ferrari S, Pearson RB, Siegmann M, Kozma SC, Thomas G. The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sites. J Biol Chem 1993;268(6):4530–4533.
PubMed
Google Scholar
Sunnarborg SW, Hinkle CL, Stevenson M, et al. Tumor necrosis factor-α converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability. J Biol Chem 2002; 277(15):12838–12845 (2002).
Article
PubMed
CAS
Google Scholar
Ko TK, Kelly E, Pines J. CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles. J Cell Sci 2001; 114:2591–2603 (2001).
PubMed
CAS
Google Scholar
Marques F, Moreau JL, Peaucellier G, et al. A new subfamily of high molecular mass CDC2-related kinases with PITAI/VRE motifs. Biochem Biophys Res Commun 2000;279(3): 832–837 (2000).
Article
PubMed
CAS
Google Scholar
Lapidot-Lifson Y, Patinkin D, Prody CA, et al. Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proc Natl Acad Sci USA 1992;89(2):579–583.
Article
PubMed
CAS
Google Scholar
Hauck CR, Sieg DJ, Hsia DA, Loftus JC, Gaarde WA, Monia BP, Schlaepfer DD. Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Cancer Res 2001; 61(19):7079–7090.
PubMed
CAS
Google Scholar
Lu L, Han AP, Chen JJ. Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses. Mol Cell Biol 2001; 12:4016–4031.
Article
Google Scholar
Weed SA, Parsons JD. Cortactin: coupling membrane dynamics to cortical actin assembly. Oncogene 2001;20:6418–6434.
Article
PubMed
CAS
Google Scholar
Campbell DH, Sutherland RL, Daly RJ. Signaling pathways and structural domains required for phosphorylation of EMSq/cortactin. Cancer Res 1999;59:5376–5385.
PubMed
CAS
Google Scholar
Mariner DJ. Identification of Src phosphorylation sites in the catenin p120ctn. J Biol Chem 2001;276:28006–28013.
Article
PubMed
CAS
Google Scholar
Lu Q. δ-catenin, an adhesive junction-associated protein which promotes cell scattering. J Cell Biol 1999;144:519–532.
Article
PubMed
CAS
Google Scholar