Skip to main content

Advertisement

Table 1 Clinical and biological status of childhood pre-B2 ALL patients

From: Proteomic profile of pre - B2 lymphoblasts from children with acute lymphoblastic leukemia (ALL) in relation with the translocation (12; 21)

Group of ALL patients Patients ID Age at diagnosis (Months) Peripheral blood lymphocytes (Giga/L) Karyotype Fusion transcripts Outcome
With t(12; 21) BACYO 24 48,7 t(12; 21) ETV6/RUNX1 CR1
GUEKE 118 42,2 t(12; 21) ETV6/RUNX1 CR1
LECRO 76 5,4 t(12; 21) ETV6/RUNX1 CR1
MARLE 42 166 t(12; 21) ETV6/RUNX1 CR1
PELAD 50 20 t(12; 21) ETV6/RUNX1 Dead*
RIFEM 76 216 t(12; 21) ETV6/RUNX1 CR1
Other karyotype abnormalities BOILE 18 2,8 dic(9;20) NA CR1
CREBA 180 11,6 mono 21 NA CR1
DESNA 13 15,5 rear9p NA CR1
JUGEL 34 8,5 Hyperploidy NA CR1
LEMAL 48 56 t(9; 22) BCL/ABL1 CR1
MORLU 171 171 t(9; 22) BCL/ABL1 Dead*
ROSLO 57 6,1 Hyperploidy NA CR1
  1. The bold numbers indicates values higher the threshold of FRALLE 2000 protocol. CR1 = First complete remission; dic = dicentric; ID = Identification; mono = monosomy; NA = Not applicable; rear = Rearrangement. * = Directly related to the recurrence of ALL.