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Table 1 Clinical and biological status of childhood pre-B2 ALL patients

From: Proteomic profile of pre - B2 lymphoblasts from children with acute lymphoblastic leukemia (ALL) in relation with the translocation (12; 21)

Group of ALL patients

Patients ID

Age at diagnosis (Months)

Peripheral blood lymphocytes (Giga/L)

Karyotype

Fusion transcripts

Outcome

With t(12; 21)

BACYO

24

48,7

t(12; 21)

ETV6/RUNX1

CR1

GUEKE

118

42,2

t(12; 21)

ETV6/RUNX1

CR1

LECRO

76

5,4

t(12; 21)

ETV6/RUNX1

CR1

MARLE

42

166

t(12; 21)

ETV6/RUNX1

CR1

PELAD

50

20

t(12; 21)

ETV6/RUNX1

Dead*

RIFEM

76

216

t(12; 21)

ETV6/RUNX1

CR1

Other karyotype abnormalities

BOILE

18

2,8

dic(9;20)

NA

CR1

CREBA

180

11,6

mono 21

NA

CR1

DESNA

13

15,5

rear9p

NA

CR1

JUGEL

34

8,5

Hyperploidy

NA

CR1

LEMAL

48

56

t(9; 22)

BCL/ABL1

CR1

MORLU

171

171

t(9; 22)

BCL/ABL1

Dead*

ROSLO

57

6,1

Hyperploidy

NA

CR1

  1. The bold numbers indicates values higher the threshold of FRALLE 2000 protocol. CR1 = First complete remission; dic = dicentric; ID = Identification; mono = monosomy; NA = Not applicable; rear = Rearrangement. * = Directly related to the recurrence of ALL.